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REACT & CARE

REsearch    

Molecular Cloning

  • Cloning
  • Sequencing
  • Mutagenesis
  • Transcription analysis
  • Differential display

 

Antibodies    

  • Construction and screening of phage display libraries
  • Generation of full-length monoclonal anti­bodies
  • Construction of antibody-fragments
  • (Fluorescence)-labelling of proteins (anti­bodies)
  • Innovative immunization technologies
  • Fusion proteins
  • ELISA construction

Analytics    

Analytical Standard Techniques
Standard & Sophisticated Methods, e.g.

  • Electrophoresis (IEF, PAGE, 2-D-DIGE)
  • Chromatography (e.g. RP-LC, GC, gelfiltration)
  • Peptide mapping
  • ELISA

 

Sophisticated Technologies (selection only)

  • Microarray technology
  • 3-Dimensional imaging
  • Confocal microscopy
  • Radioisotope image detection
  • High-throughput cell screening
  • Protein crystallography
  • Electrospray MS, MS/MS protein identification
  • Thermal analysis

Consulting    

  • GMP consulting
  • Regulatory intelligence and support (e.g. for preparation of CMC-part)
  • Sterile manufacturing technology
  • Viral safety
  • Support in market analysis and commercial­ization

Technology    

Feasibility Studies    

  • Selection of the strain from a broad spectrum of production systems (bacteria, yeasts, mammalian cells)   
  • Optimization of the strain and the fermenta­tion conditions
  • Development and optimization of the down-stream processing (purification)